Molecular epidemiology of human respiratory syncytial virus

被引：19
|
作者：
Cane, PA
Pringle, CR
机构：
[1] Department of Biological Sciences, University of Warwick, Coventry
来源：
SEMINARS IN VIROLOGY | 1995年 / 6卷 / 06期
基金：
英国惠康基金; 英国医学研究理事会;
关键词：
respiratory syncytial virus; molecular epidemiology;
D O I：
10.1016/S1044-5773(05)80014-9
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Human respiratory syncytial virus (HuRSV) is the major viral cause of severe lower respiratory tract disease in babies and infants with epidemics occurring annually in the winter in temperate climates. Analysis of the antigenic and genetic variability of HuRSV isolates has shown that there are two groups of the virus and that each group can be further subdivided into a number of genotypes in which the attachment protein shows the greatest variability together with progressive change. Epidemics are made up of multiple genotypes whose proportions vary from year to year. The various genotypes cocirculate with very similar viruses distributed world-wide.
引用
收藏
页码：371 / 378
页数：8
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