PROCERAGENIN, AN ANTIBACTERIAL CARDENOLIDE FROM CALOTROPIS-PROCERA

被引：41
|
作者：
AKHTAR, N
MALIK, A
ALI, SN
KAZMI, SU
机构：
[1] UNIV KARACHI,HEJ RES INST CHEM,KARACHI 75270,PAKISTAN
[2] UNIV KARACHI,IIDRL,DEPT MICROBIOL,KARACHI 75270,PAKISTAN
来源：
PHYTOCHEMISTRY | 1992年 / 31卷 / 08期
关键词：
CALOTROPIS-PROCERA; ASCLEPIADACEAE; CARDENOLIDE; PROCERAGENIN; ANTIBACTERIAL ACTIVITY;
D O I：
10.1016/0031-9422(92)83639-G
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new cardenolide, proceragenin, has been isolated from Calotropis procera. Its structure was determined as 7-beta,14-beta-dihydroxy-5-alpha-card-20(22)-enolide through spectroscopic studies including 2D NMR and NOE difference measurement. Its biological screening showed antibacterial activity against both Gram positive and Gram negative bacteria.
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页码：2821 / 2824
页数：4
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