PROTEIN SECONDARY STRUCTURE DETERMINATION BY NMR - APPLICATION WITH RECOMBINANT HUMAN CYCLOPHILIN

被引：65
|
作者：
WUTHRICH, K [1 ]
SPITZFADEN, C [1 ]
MEMMERT, K [1 ]
WIDMER, H [1 ]
WIDER, G [1 ]
机构：
[1] SANDOZ PHARMA AG, PRAKLIN FORSCH, CH-4002 BASEL, SWITZERLAND
来源：
FEBS LETTERS | 1991年 / 285卷 / 02期
关键词：
PROTEIN STRUCTURE; SECONDARY STRUCTURE; NUCLEAR MAGNETIC RESONANCE; NMR STRUCTURE; CYCLOPHILIN;
D O I：
10.1016/0014-5793(91)80808-G
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
It is a unique trait of the NMR method for protein structure determination that a description of the polypeptide secondary structure can be obtained at an early stage and quite independently of the complete structure calculation. In this paper the procedures used for secondary structure determination are reviewed and placed in perspective relative to the other steps in a complete three-dimensional structure determination. As an illustration the identification of the regular secondary structure elements in human cyclophilin is described.
引用
收藏
页码：237 / 247
页数：11
相关论文
共 50 条
  • [41] NMR-based automated protein structure determination
    Wuerz, Julia M.
    Kazemi, Sina
    Schmidt, Elena
    Bagaria, Anurag
    Guentert, Peter
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2017, 628 : 24 - 32
  • [42] Improving the efficiency of protein structure determination from NMR
    Kirnarsky, L
    Shats, O
    Sherman, S
    JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 1997, 419 : 213 - 220
  • [43] Membrane protein structure determination by solid state NMR
    Watts, A
    Burnett, IJ
    Glaubitz, C
    Gröbner, G
    Middleton, DA
    Spooner, PJR
    Watts, JA
    Williamson, PTF
    NATURAL PRODUCT REPORTS, 1999, 16 (04) : 419 - 423
  • [44] Microgram-scale protein structure determination by NMR
    James M Aramini
    Paolo Rossi
    Clemens Anklin
    Rong Xiao
    Gaetano T Montelione
    Nature Methods, 2007, 4 : 491 - 493
  • [45] Microgram-scale protein structure determination by NMR
    Aramini, James M.
    Rossi, Paolo
    Anklin, Clemens
    Xiao, Rong
    Montelione, Gaetano T.
    NATURE METHODS, 2007, 4 (06) : 491 - 493
  • [46] NMR METHOD FOR PROTEIN-STRUCTURE DETERMINATION IN SOLUTION
    WUTHRICH, K
    PROTEIN STRUCTURE AND ENGINEERING, 1989, 183 : 69 - 78
  • [47] Automated protein structure determination from NMR spectra
    Lopez-Mendez, Blanca
    Guntert, Peter
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (40) : 13112 - 13122
  • [48] The Ramachandran plot and the NMR method for protein structure determination
    Wiithrich, Kurt, 1600, Indian Academy of Sciences (59): : 17 - 18
  • [49] Improving the efficiency of protein structure determination from NMR
    J Molec Struct, 419 (213):
  • [50] MULTIDIMENSIONAL NMR EXPERIMENTS FOR PROTEIN-STRUCTURE DETERMINATION
    KAY, LE
    MUHANDIRAM, DR
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 254 - 254
12345