PATHOGENESIS OF PITUITARY CUSHINGS-SYNDROME - PITUITARY VERSUS HYPOTHALAMIC

被引：19

作者：

BILLER, BMK ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, DEPT MED, BOSTON, MA USA

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 1994年 / 23卷 / 03期

关键词：

D O I：

10.1016/S0889-8529(18)30083-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There has been a long-standing controversy as to whether Cushing's disease is caused by hypothalamic dysregulation or by a primary pituitary defect. There have been data supporting both concepts. Recent molecular biology techniques have confirmed, however, that coricotroph adenomas are monoclonal, supporting a genetic defect at the level of the pituitary as the cause of the disorder in most cases.

引用

页码：547 / 554

页数：8

共 50 条

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