Management of Carbapenemase-Producing Enterobacteriaceae in Intensive Care Unit

被引：0

作者：

Mootien, J. Y. ^{[1
]}

Zahar, J-R ^{[2
,3
]}

机构：

[1] Grp Hosp Reg Mulhouse & Sud Alsace, Unite Conseil Antibiotherapie, Serv Reanimat Med, 20 Ave Docteur Rene Laennec, F-68100 Mulhouse, France

[2] Univ Paris XIII, Sorbonne Paris Cite, UMR 1137, IAME, Villetaneuse, France

[3] Grp Hosp Paris Seine St Denis, AP HP, Unite Controle & Prevent Risque Infect, Dept Microbiol Clin, 125 Rue Stalingrad, F-93000 Bobigny, France

来源：

REANIMATION | 2018年 / 27卷 / 04期

关键词：

Carbapenemase-producing Enterobacteriaceae; Multidrug-resistant bacteria; Infection control measures; Combination therapy; Future therapeutic options;

D O I：

10.3166/rea-2018-0058

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infections due to carbapenemase-producing enterobacteriaceae may represent a potential threat due to the scarcity of the available therapeutic resources. OXA-48 and OXA-48-like are most prevalent in France. Older agents have become the last resort choices as treatment options are relatively few and combination therapy with optimal administration should be considered. Therapeutic future options as well as randomized controlled trials are needed. Meanwhile, we need to look at experiences of those managing this health problem and promoting better use of antibiotics stands as a sheer necessity.

引用

页码：372 / 380

页数：9

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