SECRETION AND MOVEMENT OF WINGLESS PROTEIN IN THE EPIDERMIS OF THE DROSOPHILA EMBRYO

被引：227

作者：

GONZALEZ, F ^{[1
]}

SWALES, L ^{[1
]}

BEJSOVEC, A ^{[1
]}

SKAER, H ^{[1
]}

ARIAS, AM ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT ZOOL,AFRC,MOLEC SIGNALLING LAB,CAMBRIDGE CB2 3EJ,ENGLAND

来源：

MECHANISMS OF DEVELOPMENT | 1991年 / 35卷 / 01期

基金：

英国惠康基金;

关键词：

DROSOPHILA; WINGLESS; SECRETION; PATTERN FORMATION;

D O I：

10.1016/0925-4773(91)90040-D

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The segment polarity gene wingless encodes a cysteine rich protein which is essential for pattern formation in Drosophila. Using polyclonal antibodies against the product of the wingless gene, we demonstrate that this protein is secreted in the embryo and that it is taken up by neighbouring cells. The protein can be found two or three cell diameters away from the cells in which it is synthesized. We discuss the possible mechanisms which are responsible for this spatial distribution and its regulation during embryogenesis.

引用

页码：43 / 54

页数：12

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