RADIATION-INDUCED MICRENCEPHALY IN GUINEA-PIGS

被引：1
|
作者：
WAGNER, LK
JOHNSTON, DA
FELLEMAN, DJ
机构：
[1] UNIV TEXAS,MD ANDERSON CANCER CTR,DEPT BIOMATH,HOUSTON,TX 77030
[2] UNIV TEXAS,DEPT NEUROBIOL & ANAT,HOUSTON,TX 77030
来源：
RADIATION RESEARCH | 1992年 / 132卷 / 01期
关键词：
D O I：
10.2307/3578333
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The effect of X rays on brain weight of guinea pig pups at birth was studied in 21-day-old embryos exposed in utero to doses of 75 and 100 mGy. When compared to controls and when corrected for body weight, gestation time, litter size, sex, and examiner differences, the brains of irradiated pups weighed approximately 46 mg less than those of controls (P < 0.001) for the 75-mGy group and about 55 mg less for the 100-mGy group. Brains of females weighed 51 mg less than those of males of the same body weight. Dam weight and caging conditions had no observed effect on brain weight.
引用
收藏
页码：54 / 60
页数：7
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