Acneiform Rash Caused by an Unlikely Drug: Topiramate

被引:3
|
作者
Bello-Hernandez, Yesenia [1 ]
Espinoza-Hernandez, Jessica [2 ]
Moreno-Coutino, Gabriela [1 ]
机构
[1] Hosp Gen Dr Manuel Gea Gonzalez, Secc Micol, Calzada Tlalpan 4800,Secc 16, Mexico City 14080, DF, Mexico
[2] Hosp Gen Dr Manuel Gea Gonzalez, Secc Dermatopatol, Mexico City, DF, Mexico
关键词
Topiramate; Migraine; Adverse event; Rash;
D O I
10.1159/000477742
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Topiramate is an antiepileptic drug that can also be used for migraine prophylaxis, weight control, and even for methamphetamine dependence; the dosage margin is wide, and the list of side effects is shorter than with other anticonvulsants. We present the case of a 35-year-old man with a disseminated rash of the trunk and extremities after treatment with 25 mg of topiramate daily as a prophylactic migraine treatment. This case report is useful, as this patient was not polymedicated and had a score of 7 on the Naranjo Adverse Drug Reaction Probability Scale. The patient was diagnosed as atypical DRESS syndrome and resolved satisfactorily with symptomatic treatment and topiramate withdrawal; slowly, the lesions regressed. He required no further drugs for the dermatologic condition. (c) 2017 S. Karger AG, Basel
引用
收藏
页码:25 / 28
页数:4
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