MONITORING HEPATITIS-B VIRUS-REPLICATION

被引：3
|
作者：
KUHNS, MC
机构：
[1] Diagnostics Division, Abbott Laboratories, North Chicago, IL
来源：
JOURNAL OF HEPATOLOGY | 1990年 / 11卷
关键词：
D O I：
10.1016/0168-8278(90)90171-M
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Serum hepatitis B virus DNA is the best marker for monitoring hepatitis B virus replication in the liver. Data are presented on the sensitivity, specificity and application of a standardized solution hybridization assay for the quantitation of hepatitis B viral DNA in serum. The assay is linear over several orders of magnitude in sample concentration and is equivalent in sensitivity and specificity to classic filter hybridization methods employing [P-32]DNA probes and autoradiography. The assay provides clinically relevant information for monitoring viral replication before, during and after antiviral therapy.
引用
收藏
页码：S90 / S94
页数：5
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