ANALYSIS OF HUMAN T-CELL RECEPTOR ALPHA-CHAIN CDNAS ISOLATED FROM PERIPHERAL-BLOOD MONONUCLEAR-CELLS

被引：6
|
作者：
YASSAI, M [1 ]
BULL, M [1 ]
GORSKI, J [1 ]
机构：
[1] BLOOD CTR SE WISCONSIN INC,BLOOD RES INST,IMMUNOGENET RES SECT,1701 W WISCONSIN AVE,MILWAUKEE,WI 53233
来源：
HUMAN IMMUNOLOGY | 1992年 / 34卷 / 04期
关键词：
D O I：
10.1016/0198-8859(92)90027-K
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
T-cell receptor alpha-chain cDNA were generated from unstimulated peripheral blood mononuclear cells of a DR2,3,52a individual using a modified anchor PCR method. Fifty-six cDNA clones were identified representing 47 distinct T-cell receptor clonotypes and 26 VA loci. This analysis identified a new VA gene family VA30, and a new member of the VA6 gene family.
引用
收藏
页码：279 / 283
页数：5
相关论文
共 50 条
  • [1] T-CELL SUBSET ANALYSIS OF CRYOPRESERVED HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    LUDGATE, ME
    DRYDEN, PR
    WEETMAN, AP
    MCGREGOR, AM
    IMMUNOLOGY LETTERS, 1983, 7 (03) : 119 - 122
  • [2] HUMAN-ALPHA AND HUMAN-BETA T-CELL RECEPTOR GENE REARRANGEMENT IN PERIPHERAL-BLOOD MONONUCLEAR-CELLS OF HEALTHY-INDIVIDUALS AND PATIENTS WITH T-CELL MALIGNANCIES
    LANEUVILLE, P
    FAUSER, AA
    PRICE, GB
    CLINICAL RESEARCH, 1986, 34 (02): : A462 - A462
  • [3] INDUCTION OF HUMAN IMMUNE INTERFERON FROM PERIPHERAL-BLOOD MONONUCLEAR-CELLS INDUCED WITH COMBINATIONS OF T-CELL MITOGENS
    TSUJIMOTO, M
    HIGASHI, N
    METHODS IN ENZYMOLOGY, 1986, 119 : 93 - 95
  • [4] DELINEATION OF CANINE PARVOVIRUS T-CELL EPITOPES WITH PERIPHERAL-BLOOD MONONUCLEAR-CELLS AND T-CELL CLONES FROM IMMUNIZED DOGS
    RIMMELZWAAN, GF
    POELEN, MCM
    MELOEN, RH
    CARLSON, J
    UYTDEHAAG, FGCM
    OSTERHAUS, ADME
    JOURNAL OF GENERAL VIROLOGY, 1990, 71 : 2321 - 2329
  • [5] INTRACELLULAR METABOLISM OF 3'-AZIDOTHYMIDINE IN ISOLATED HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    TORNEVIK, Y
    JACOBSSON, B
    BRITTON, S
    ERIKSSON, S
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 1991, 7 (09) : 751 - 759
  • [6] ESTERASE STAINING OF HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    DEJONG, MCJM
    JOURNAL OF IMMUNOLOGICAL METHODS, 1979, 26 (02) : 193 - 196
  • [7] DISTRIBUTION OF INTEGRINS ON HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    KLINGEMANN, HG
    DEDHAR, S
    BLOOD, 1989, 74 (04) : 1348 - 1354
  • [8] COLLAGENASE PRODUCTION BY HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    SIMPSON, JW
    MACKLER, BF
    ONEILL, PA
    MAILMAN, ML
    ADAMS, S
    HARRIS, J
    JOURNAL OF DENTAL RESEARCH, 1978, 57 : 264 - 264
  • [9] THE UTILIZATION OF GLUCOSE BY HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    STEWART, CC
    IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION, 1980, 16 (03): : 257 - 257
  • [10] ELASTOLYTIC ACTIVITY OF HUMAN PERIPHERAL-BLOOD MONONUCLEAR-CELLS
    FINE, R
    COLLINS, JF
    CLINICAL RESEARCH, 1980, 28 (02): : A424 - A424
12345