THE USE OF BETA BLOCKER NEBIVOLOL IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN ASSOCIATION WITH ARTERIAL HYPERTENSION

被引：0
|
作者：
Martiniuc, C. [1 ]
Branishte, T. [2 ]
机构：
[1] IMSP Inst Phtisiopneumol, Chiril Draganiuc Chishinau, Chishinau, Moldova
[2] State Med & Pharmaceut Univ Nicolae Testemitanu C, Chishinau, Moldova
来源：
MEDICAL-SURGICAL JOURNAL-REVISTA MEDICO-CHIRURGICALA | 2012年 / 116卷 / 01期
关键词：
BRONCHIAL PERMEABILITY; ARTERIAL HYPERTENSION; BETA-BLOCKER; ENDOTHELIAL FUNCTION; MEAN PRESSURE;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
There were investigated 22 patients with chronic obstructive pulmonary disease in association with arterial hypertension initially and after 5 weeks of treatment with beta-blocker Nebivolol 5 mg/day. There were not detected any negative changes on bronchial permeability after treatment. Considerable improvement of endothelial function (from 7-12% to 17-35%, p<0.05) in parallel with decreasing of pulmonary artery, systolic (44.5 +/- 5.5 mmHg vs. 32.8 +/- 4.1 mmHg, p<0.05) and mean pressure (26.3 +/- 4.2 mmHg vs. 21.1 +/- 2.1 mmHg, p<0.05) - were observed after treatment. Thus, Nebilet is well-tolerated and highly effective in patients with chronic obstructive pulmonary disease in association with arterial hypertension.
引用
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页码：218 / 221
页数：4
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