LACK OF TOXICITY OF INTRAVITREALLY ADMINISTERED INTERFERON ALPHA-2A

被引：0
|
作者：
KARACORLU, MA [1 ]
PEYMAN, GA [1 ]
CRUZ, S [1 ]
SOIKE, KF [1 ]
机构：
[1] DELTA REG PRIMATE RES CTR,COVINGTON,LA 70433
来源：
OPHTHALMIC SURGERY AND LASERS | 1992年 / 23卷 / 12期
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D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
We investigated the toxicity of single doses of intravitreally administered interferon alpha-2a in albino rabbits. Following injection of interferon in doses of 40 000, 80 000, 160 000, 320 000, and 640 000 IU/0.1 mL, no significant histologic changes were detected by light and electron microscopy. Photopic and scotopic electroretinography showed no alteration of retinal function.
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页码：833 / 835
页数：3
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