NEUTRAL GLYCOLIPIDS AND GANGLIOSIDES OF CONCANAVALIN-A-SELECTED SV3T3 REVERTANT CELLS AND OF NORMAL AND SV40-TRANSFORMED BALB-C 3T3-CELLS

被引：10
|
作者：
MUGNAI, G [1 ]
COPPINI, R [1 ]
TOMBACCINI, D [1 ]
FALLANI, A [1 ]
RUGGIERI, S [1 ]
机构：
[1] UNIV FLORENCE, INST GEN PATHOL, I-50121 FLORENCE, ITALY
来源：
BIOCHEMICAL JOURNAL | 1981年 / 193卷 / 03期
关键词：
D O I：
10.1042/bj1931025
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The structural analysis of neutral glycolipids and gangliosides of the SV40-transformed Balb/c3T3 cells (SV3T3 cells) and concanavalin A-selected SV3T3 revertant cells, compared with untransformed Balb/c3T3 cells, has shown: a content of neutral glycolipids in revertant cells near to that found in the untransformed parental cells, a similar decrease of the higher gangliosides in transformed and revertant cells and a content of ganglioside GM3 in revertant cells much higher than that found in SV3T3 and untransformed Balb/c3T3 cells. The possible role of ganglioside GM3 in growth control is discussed.
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页码：1025 / 1028
页数：4
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