INCIDENCE AND RISK-FACTORS ASSOCIATED WITH ABNORMAL POSTPARTUM GLUCOSE-TOLERANCE IN WOMEN WITH GESTATIONAL DIABETES

被引:116
|
作者
CATALANO, PM [1 ]
VARGO, KM [1 ]
BERNSTEIN, IM [1 ]
AMINI, SB [1 ]
机构
[1] UNIV VERMONT,COLL MED,DEPT OBSTET & GYNECOL,BURLINGTON,VT 05405
关键词
POSTPARTUM GLUCOSE TOLERANCE; GESTATIONAL DIABETES;
D O I
10.1016/0002-9378(91)90438-W
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
To determine the incidence and risk factors associated with an abnormal postpartum glucose tolerance in women with gestational diabetes, 103 patients with gestational diabetes had a 2-hour, 75 gm oral glucose tolerance test 6 +/- 2 weeks (mean +/- SD) after delivery. Twenty-two percent (23/103) of results were abnormal: Three showed frank diabetes, four showed impaired glucose tolerance, and 16 were nondiagnostic. There was a significant difference in gravidity, pregravid weight and body mass index, delivery weight, gestational age at diagnosis, fasting and 2- and 3-hour glucose level at the time of the oral glucose tolerance test during pregnancy, need for insulin therapy during gestation, and neonatal weight > 4000 gm in the abnormal group as compared with the normal group. Elevated fasting glucose level (p = 0.0001) and earlier gestational age at time of diagnosis of gestational diabetes (p = 0.013) were found to be most predictive of an abnormal postpartum glucose tolerance test result. These results support the importance of postpartum oral glucose tolerance testing in women with gestational diabetes.
引用
收藏
页码:914 / 919
页数:6
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