REFRACTORINESS OF ERYTHROCYTES INFECTED WITH PLASMODIUM-FALCIPARUM GAMETOCYTES TO LYSIS BY SORBITOL

被引：25
|
作者：
SAUL, A
GRAVES, P
EDSER, L
机构：
[1] Queensland Institute of Medical Research, Brisbane, QLD 4006, Bramston Terrace, Herston
来源：
INTERNATIONAL JOURNAL FOR PARASITOLOGY | 1990年 / 20卷 / 08期
基金：
英国医学研究理事会;
关键词：
PLASMODIUM-FALCIPARUM; GAMETOCYTES; SCHIZONTS; SORBITOL LYSIS; SYNCHRONIZATION;
D O I：
10.1016/0020-7519(90)90056-S
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Unlike erythrocytes infected with mature asexual parasites of Plasmodium falciparum, those infected with gametocytes are not lysed by 5% sorbitol solutions. This observation was used to devise a method for producing synchronized cultures of gametocytes, free of asexual stage parasites. The refractoriness to sorbitol suggests that the major anion transport pathway, which appears in the membrane of erythrocytes infected with asexual stage parasites, is not present in cells infected with gametocytes.
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页码：1095 / 1097
页数：3
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