Tumor necrosis factor-alpha concentrations in preeclamptic and healthy normotensive pregnant patients

被引：0
|
作者：
Reyna-Villasmil, E. [1 ]
Mejia-Montilla, J. [1 ]
Reyna-Villasmil, N. [1 ]
Torres-Cepeda, D. [1 ]
Santos-Bolivar, J. [1 ]
Perozo-Romero, J. [1 ]
机构：
[1] Hosp Cent Dr Urquinaona, Serv Obstet & Ginecol, Maternidad Dr Nerio Belloso, Maracaibo, Estado Zulia, Venezuela
来源：
CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA | 2012年 / 39卷 / 06期
关键词：
Tumor necrosis factor alpha; Preeclampsia; Cytokines;
D O I：
10.1016/j.gine.2009.12.014
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To compare tumor necrosis factor-alpha concentrations in patients with preeclampsia and healthy normotensive pregnant women. Material And Methods: One hundred patients were selected. Fifty preeclamptic patients were selected as cases (group A) and 50 healthy pregnant women with a similar age and body mass index to patients in group A were selected as controls (group B). Blood samples for tumor necrosis factor-alpha determination were collected in all patients before labor and immediately after diagnosis in the study group. Results: There were no significant differences in maternal age, gestational age or body mass index at sample collection (p=ns). Statistically significant differences were found between groups in mean values of systolic and diastolic blood pressure (p<0.05). Significant differences were found in tumor necrosis factor-alpha concentrations in group A (9.7 +/- 4.6 pg/ml) and patients in group B ( 5.5 +/- 1.6 pg/ml; p<0.05), and a moderate, positive and significant correlation was found with mean systolic (r=0.433; p<0.05) and diastolic (r=0.412; p<0.05) blood pressure. Conclusions: Tumor necrosis factor-alpha concentrations were significantly higher in preeclamptic patients than in healthy normotensive pregnant women. (C) 2009 Elsevier Espana, S.L. All rights reserved.
引用
收藏
页码：236 / 240
页数：5
相关论文
共 50 条
  • [1] Tumor necrosis factor alpha and Doppler velocimetry of the uterine arteries in preeclamptic patients and healthy normotensive pregnant women
    Reyna-Villasmil, E.
    Mejia-Montilla, J.
    Santos-Bolivar, J.
    Torres-Cepeda, D.
    Navarro-Briceno, Y.
    Aragon-Charry, J.
    Reyna-Villasmil, N.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2015, 42 (01): : 7 - 12
  • [2] Interleukin 10 concentrations in preeclamptic and healthy normotensive pregnant patients
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres-Cepeda, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2011, 38 (05): : 164 - 168
  • [3] Interleukin-8 concentrations in preeclamptic and healthy normotensive pregnant patients
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2012, 39 (05): : 182 - 186
  • [4] Interleukin-2 concentrations in preeclamptic and healthy normotensive pregnant patients
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2012, 39 (02): : 48 - 52
  • [5] Interleukin-13 concentrations in preeclamptic and healthy normotensive pregnant patients
    Reyna-Villasmil, E.
    Mejia-Montilla, J.
    Reyna-Villasmil, N.
    Torres-Cepeda, D.
    Santos-Boliva, J.
    Perozo-Romero, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2013, 40 (01): : 15 - 19
  • [6] Interleukin-15 concentrations in preeclamptic and healthy normotensive pregnant patients
    Reyna-Villasmil, E.
    Mejia-Montilla, J.
    Reyna-Villasmil, N.
    Torres-Cepeda, D.
    Santos-Bolivar, J.
    Aragon-Charris, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2013, 40 (03): : 115 - 119
  • [7] Interleucin 1 beta concentrations in preeclamptic patients and healthy normotensive pregnant women
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2011, 38 (04): : 128 - 132
  • [8] Interferon-gamma concentrations in preeclamptic patients and healthy normotensive pregnant women
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2012, 39 (03): : 108 - 112
  • [9] Interleukin-6 concentrations in preeclamptic and healthy normotensive pregnant women
    Reyna, E.
    Mejia, J.
    Reyna, N.
    Torres, D.
    Santos, J.
    Perozo, J.
    CLINICA E INVESTIGACION EN GINECOLOGIA Y OBSTETRICIA, 2012, 39 (04): : 159 - 163
  • [10] Tumor necrosis factor-α in whole blood cultures of preeclamptic patients and healthy pregnant and nonpregnant women
    Beckmann, I
    Ben Efraim, S
    Vervoort, M
    Visser, W
    Wallenburg, HCS
    HYPERTENSION IN PREGNANCY, 2004, 23 (03) : 319 - 329
12345