IMMUNOGLOBULIN-G, IMMUNOGLOBULIN-A AND IMMUNOGLOBULIN-M LIGHT CHAIN RATIO IN CHILDREN

被引：9
|
作者：
HARALDSSON, A
WEEMAES, CMR
KOCKJANSEN, MJH
VONECKARTS, PBJM
DEBOO, T
BAKKEREN, JAJM
STOELINGA, GBA
机构：
[1] UNIV HOSP NIJMEGEN,DEPT PAEDIAT,NIJMEGEN,NETHERLANDS
[2] UNIV HOSP NIJMEGEN,CENT CLIN CHEM LAB,NIJMEGEN,NETHERLANDS
[3] UNIV HOSP NIJMEGEN,DEPT MED STAT,NIJMEGEN,NETHERLANDS
来源：
ANNALS OF CLINICAL BIOCHEMISTRY | 1992年 / 29卷
基金：
美国国家科学基金会;
关键词：
KAPPA CHAINS; LAMBDA CHAINS; REFERENCE VALUES;
D O I：
10.1177/000456329202900303
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Values for the kappa/lambda-light chain ratio in immunoglobulins G, A and M and the total kappa/lambda-ratio, measured by enzyme linked immunosorbent assay, were evaluated in serum samples from different age groups (114 children, aged from 1 month to 15 years, and 20 adults). The IgG kappa/lambda-ratio decreased in the first 6 months and subsequently increased slowly during childhood towards the adult value of 2.0. The IgM kappa/lambda-ratio increased at a greater rate than IgG kappa/lambda-ratio in the first years of life and thereafter rose slightly throughout childhood to reach an adult value of 1.7. A decreasing IgA kappa/lambda-ratio was found from 1 month of age onwards to an adult value of 1.1. The pattern of total kappa/lambda-ratio was similar to the IgG kappa/lambda-ratio with an adult value of 2.0.
引用
收藏
页码：271 / 274
页数：4
相关论文
共 50 条
12345