EXPEDIENT SYNTHETIC ROUTES TO [H-3] D-3-AZIDO-3-DEOXY-MYO-INOSITOL AND D-3-AZIDO-3-DEOXY-MYO-INOSITOL 2,4,5-TRISPHOSPHATE

被引:15
|
作者
KOZIKOWSKI, AP
FAUQ, AH
POWIS, G
KURIAN, P
CREWS, FT
机构
[1] MAYO CLIN & MAYO FDN,DEPT PHARMACOL,ROCHESTER,MN 55905
[2] UNIV FLORIDA,J HILLIS MILLER HLTH CTR,GAINESVILLE,FL 32610
关键词
D O I
10.1039/c39920000362
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Expedient routes to a tritiated derivative of the v-sis oncogene-transformed cell specific growth inhibitor 3-azido-3-deoxy-myo-inositol and the unlabelled 2,4,5-trisphosphate derivative are described together with the effects of the latter compound in binding to the IP3 receptor.
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页码:362 / 364
页数:3
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