A STUDY ON CLINICAL PROFILE AND COMPLICATIONS OF LEPTOSPIROSIS AT KILPAUK MEDICAL COLLEGE, CHENNAI

BACKGROUND Leptospirosis is associated with characteristic symptoms, signs and functional alterations in many organs and systems. The purpose of this study was to analyse functional changes in many organs and systems and to determine outcome and complications. AIMS AND OBJECTIVES 1. To study and analyse clinical profiles and complications of leptospirosis. 2. To study biochemical profile of leptospirosis. MATERIALS AND METHODS This study was carried out in medical wards at Kilpauk Medical College, Chennai, from January 2015 to August 2015; 67 patients were diagnosed with leptospirosis and who fulfilled the inclusion criteria were included in the study and the required data were collected from medical wards, IMCU and laboratory. RESULTS Out of 67 patients studied, Hepatitis was seen in 39 cases, Acute Kidney injury was seen in 31 cases, ARDS was seen in 3 cases and Myocarditis was seen in 2 cases. Out of 31 cases of Acute Kidney injury, Dialysis was done in 17 cases. Out of 31 cases of Acute Renal Failure, 2 cases died and out of 3 cases of ARDS 1 case died. CONCLUSION This study concludes that Leptospirosis cases were more prone to develop Hepatitis and Acute Kidney injury and least commonly ARDS and Myocarditis. So in spite of monitoring of Renal and Hepatic functions, screening of cardiac and respiratory function was also needed in initial diagnostic and evaluation of Leptospirosis.