SYNTHESIS OF 2-(4-CHLOROPHENYL)-4-HYDROXY-7-(4-TRIFLUOROMETHYLPHENYL)-5,6,7,8-TETRAHYDROQUINOLIN-5-ONE AND 3-(4-CHLOROPHENYL)-4-HYDROXY-7-(4-TRIFLUOROMETHYLPHENYL)-5,6,7,8-TETRAHYDROQUINOLIN-5-ONE AND 5,10-DIHYDRO-11H-8-CHLOROINDENO(1,2-B)QUINOLIN-10,11-DIONES AS ANTIMALARIALS

被引：0
|
作者：
VENUGOPALAN, B
BAPAT, CP
DESOUZA, EP
DESOUZA, NJ
机构：
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1992年 / 31卷 / 01期
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The syntheses of tetrahydroquinolin-4-hydroxy-5-ones 7 and 8 and indeno[1, 2-b]quinolin-10, 11-diones 14 and 15 using oxazinediones and isatoic anhydride respectively are reported. One of the derivatives namely 16 shows weak antimalarial activity in animal model.
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页码：35 / 38
页数：4
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