MONOCLONAL-ANTIBODIES AGAINST ANTIGENS EXPRESSED BY HUMAN SPERM

被引：0
|
作者：
ZIEGLER, A
HIRSCH, T
KRAUSE, W
NEUMANN, K
SCHIEFERSTEIN, G
DOHR, G
KOHLSTADT, S
UCHANSKAZIEGLER, B
机构：
[1] UNIV MARBURG,INST EXPTL IMMUNOL,W-3550 MARBURG,GERMANY
[2] UNIV MARBURG,MED ZENTRUM HAUTKRANKHEITEN,W-3550 MARBURG,GERMANY
[3] UNIV MARBURG,MED ZENTRUM PATHOL,W-3550 MARBURG,GERMANY
[4] UNIV TUBINGEN,HAUT KLIN,W-7400 TUBINGEN 1,GERMANY
[5] GRAZ UNIV,INST HISTOL & EMBRYOL,A-8010 GRAZ,AUSTRIA
[6] CNRS,CTR IMMUNOL,INSERM,MARSEILLE,FRANCE
来源：
ANDROLOGIA | 1990年 / 22卷
关键词：
MONOCLONAL ANTIBODIES; HUMAN SPERM ANTIGENS; IMMUNOCYTOCHEMISTRY; SPERM-LEUKOCYTE CROSS-REACTIVITY; ANTIGEN LOCALIZATION;
D O I：
暂无
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
The production and characterization of 21 mouse monoclonal antibodies (TuS1-TuS21) with specificity predominantly for human spermatozoa antigens is described. Reactivity of cells from human ejaculates, peripheral blood and several organs was determined using the alkaline phosphatase-anti-alkaline phosphatase (APAAP)-technique as well as the indirect immunofluorescence test. 15 of the monoclonal antibodies reacted with various regions of human sperm and often also with their precursor cells in the testis. Cross-reactivity with animal spermatozoa was frequently observed.
引用
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页码：101 / 109
页数：9
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