BINDING OF 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1, 4-DIAZEPIN-1-YL)BENZIMIDAZOLE DIFUMARATE (KG-2413) TO SERUM OR PLASMA-PROTEINS IN MAN, GUINEA-PIG AND RAT

被引：3

作者：

SAKAI, T ^{[1
]}

HAMADA, T ^{[1
]}

AWATA, N ^{[1
]}

WATANABE, J ^{[1
]}

机构：

[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,DEPT BIOPHARMACEUT,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

JOURNAL OF PHARMACOBIO-DYNAMICS | 1988年 / 11卷 / 04期

关键词：

D O I：

10.1248/bpb1978.11.262

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：262 / 267

页数：6

共 33 条

[1] INTERSPECIES DIFFERENCES IN PHARMACOKINETICS OF AN ANTIALLERGIC AGENT, 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1,4-DIAZEPIN-1-YL)BENZIMIDAZOLE DIFUMARATE (KG-2413) AFTER INTRAVENOUS ADMINISTRATION TO RATS, GUINEA-PIGS AND DOGS
SAKAI, T
HAMADA, T
AWATA, N
WATANABE, J
CHEMICAL & PHARMACEUTICAL BULLETIN, 1989, 37 (03) : 753 - 756
[2] IDENTIFICATION OF THE METABOLITES OF AN ANTIALLERGIC AGENT, 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1H-1,4-DIAZEPIN-1-YL)-1H-BENZIMIDAZOLE DIFUMARATE (KG-2413), IN RATS
AWATA, N
TAKAHASHI, H
NOUMI, K
SAKAI, T
HAMADA, T
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1989, 109 (05): : 318 - 328
[3] SYNTHESES OF THE METABOLITES OF 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1H-1,4-DIAZEPIN-1-YL)-1H-BENZIMIDAZOLE DIFUMARATE (KG-2413) AND RELATED-COMPOUNDS
IEMURA, R
HORI, M
OHTAKA, H
CHEMICAL & PHARMACEUTICAL BULLETIN, 1989, 37 (04) : 962 - 966
[4] CROSS-REACTIVITIES OF ACTIVE METABOLITES IN THE RADIORECEPTOR ASSAY OF AN ANTIALLERGIC AGENT, 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1H-1,4-DIAZEPIN-1-YL)-1H-BENZIMIDAZOLE DIFUMARATE (KG-2413)
HAMADA, T
KAWASHIMA, T
AWATA, N
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1989, 109 (07): : 474 - 479
[5] PHARMACOKINETICS OF AN ANTIALLERGIC AGENT, 1-(2-ETHOXYETHYL)-2-(HEXAHYDRO-4-METHYL-1H-1, 4-DIAZEPIN-1-YL)-1H-BENZIMIDAZOLE DIFUMARATE (KG-2413) AFTER ORAL-ADMINISTRATION - INTERSPECIES DIFFERENCES IN RATS, GUINEA-PIGS AND DOGS
SAKAI, T
HAMADA, T
AWATA, N
WATANABE, J
JOURNAL OF PHARMACOBIO-DYNAMICS, 1989, 12 (09): : 530 - 536
[6] ANTIALLERGIC EFFECT OF 1-(2-ETHOXYETHYL)-2-(4-METHYL-1-HOMOPIPERAZINYL)BENZIMIDAZOLE DIFUMARATE (KB-2413)
FUKUDA, T
SAITO, T
TAJIMA, S
SHIMOHARA, K
ITO, K
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-2 (07): : 805 - 810
[7] ANTIASTHMATIC EFFECT OF 1-(2-ETHOXYETHYL)-2-(4-METHYL-1-HOMOPIPERAZINYL)BENZIMIDAZOLE DIFUMARATE (KB-2413), A NEW ANTIALLERGIC
FUKUDA, T
SAITO, T
ITO, K
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-2 (07): : 811 - 815
[8] RADIORECEPTOR ASSAY FOR A NEW ANTIALLERGIC AGENT, 1-(2-ETHOXYETHYL)-2-(4-METHYL-1-HOMOPIPERAZINYL)BENZIMIDAZOLE DIFUMARATE (KB-2413), IN PLASMA
HAMADA, T
KADOWAKI, M
AWATA, N
CHEMICAL & PHARMACEUTICAL BULLETIN, 1987, 35 (08) : 3329 - 3335
[9] INFLUENCE OF 1-(2-ETHOXYETHYL)-2-(4-METHYL-1-HOMOPIPERAZINYL)BENZIMIDAZOLE DIFUMARATE (KB-2413), A NEW ANTIALLERGIC, ON CILIARY MOVEMENT
FUKUDA, T
SAITO, T
YOSHIDOMI, M
ITO, K
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-2 (07): : 816 - 818
[10] ANTIALLERGIC EFFECTS OF 1-(2-ETHOXYETHYL)-2-(4-METHYL-1-HOMOPIPERAZINYL) BENZIMIDAZOLE (KB-2413)
SAITO, T
NISHIMURA, N
TAJIMA, S
FUKUDA, T
ITO, K
FOLIA PHARMACOLOGICA JAPONICA, 1987, 89 (02) : 55 - 62

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