PERSPECTIVES IN STEROID HYDROXYLASE GENE-EXPRESSION - NOVEL SITES OF EXPRESSION DURING EMBRYONIC-DEVELOPMENT

被引：2
|
作者：
KEENEY, DS
机构：
[1] Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN
来源：
ENDOCRINE RESEARCH | 1995年 / 21卷 / 1-2期
关键词：
D O I：
10.3109/07435809509030425
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
CYP17 is not expressed in adult mouse adrenal glands but is expressed in a subset of fetal adrenocortical cells, indicating the potential to produce both corticosterone and cortisol during murine embryogenesis. CYP11A is expressed in the fetal adrenal but also in developing hindgut, which will form the colon, and in cells located beneath the skin of the embryo. Novel sites of expression of CYP17 and CYP11A in the mouse embryo suggest potential physiological roles for local production of steroids in diverse organs systems during development.
引用
收藏
页码：103 / 107
页数：5
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