CHRONIC GRANULOCYTIC-LEUKEMIA PRESENTING WITH AN EXTRAMEDULLARY T-LYMPHOBLASTIC CRISIS

被引：11
|
作者：
JACOB, A [1 ]
ROWLANDS, DC [1 ]
PATTON, N [1 ]
HOLMES, JA [1 ]
机构：
[1] QUEEN ELIZABETH HOSP,DEPT HISTOPATHOL,BIRMINGHAM B15 2TH,W MIDLANDS,ENGLAND
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1994年 / 88卷 / 02期
关键词：
CHRONIC GRANULOCYTIC LEUKEMIA; EXTRAMEDULLARY T LYMPHOBLASTIC;
D O I：
10.1111/j.1365-2141.1994.tb05050.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 33-year-old man presented with hepatosplenomegaly and lymphadenopathy. Bone marrow findings were consistent with Philadelphia-positive accelerated-phase chronic granulocytic leukaemia (CGL). Lymph node histology and immunhistochemistry were diagnostic of T lymphoblastic lymphoma. Molecular studies on lymph node DNA identified rearrangement within the major breakpoint cluster region (M-bcr), indicating a common clonal origin of CGL and the T lymphoblastic lymphoma. We report the second case where extramedullary T lymphoblastic crisis was the presenting feature of CGL.
引用
收藏
页码：435 / 436
页数：2
相关论文
共 50 条
  • [1] Bilineage T-lymphoblastic/myeloid extramedullary blast crisis in chronic myelogenous leukemia
    Nair, Indu M.
    Feroze, M.
    Aravindan, K. P.
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2016, 59 (01) : 107 - 109
  • [2] Extramedullary T-lymphoblastic blast crisis in chronic myelogenous leukemia - a rare entity
    Paul, S.
    Morgner, C.
    Hoefers, C.
    Wickenhauser, C.
    Mueller, L. -P.
    Al-Ali, H. K.
    ONCOLOGY RESEARCH AND TREATMENT, 2017, 40 : 153 - 153
  • [3] Chronic myeloid leukemia presenting as extramedullary T- lymphoblastic crisis and extramedullary hematopoiesis
    Galvis Castro, K. T.
    Martinez Baquero, D. L.
    Saavedra Andrade, C. E.
    Andrade Perez, R. E.
    Romero Prieto, M. L.
    VIRCHOWS ARCHIV, 2024, 485 : S310 - S310
  • [4] A case of extramedullary T-lymphoblastic blast crisis as an initial presentation of chronic myelogenous leukemia
    Shen, Jing-Zhi
    Jing, Yuan
    Tian, Ye
    Jiang, Feng
    Ma, Liang-Liang
    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2021, 43 (04) : E238 - E241
  • [5] PH1-POSITIVE T-LYMPHOBLASTIC TRANSFORMATION OF CHRONIC GRANULOCYTIC-LEUKEMIA IN A LYMPH-NODE
    PALUTKE, M
    EISENBERG, L
    NATHAN, L
    LABORATORY INVESTIGATION, 1983, 48 (01) : A66 - A66
  • [6] PH1-POSITIVE T-LYMPHOBLASTIC TRANSFORMATION OF CHRONIC GRANULOCYTIC-LEUKEMIA IN A LYMPH-NODE
    PALUTKE, M
    EISENBERG, L
    NATHAN, L
    LANCET, 1982, 2 (8306): : 1053 - 1053
  • [7] TREATMENT OF CHRONIC GRANULOCYTIC-LEUKEMIA IN BLASTIC CRISIS
    CANELLOS, GP
    BONE MARROW TRANSPLANTATION, 1989, 4 : 131 - 132
  • [8] CHRONIC GRANULOCYTIC-LEUKEMIA OCCURRING IN BLAST CRISIS
    KAPADIA, SB
    KRAUSE, JR
    PAN, SF
    COTELINGAM, J
    NITIYANANT, P
    ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 1979, 103 (06) : 291 - 292
  • [9] Sudden extramedullary T-lymphoblastic blast crisis in chronic myelogenous leukemia - A nonrandom event associated with imatinib?
    Kim, Annette S.
    Goldstein, Steven C.
    Luger, Selina
    Van Deerlin, Vivianna M.
    Bagg, Adam
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2008, 129 (04) : 639 - 648
  • [10] Extramedullary T-lymphoblastic blast crisis in chronic myelogenous leukemia: A case report of successful diagnosis and treatment
    Zeng, Dong-Feng
    Chang, Cheng
    Li, Jie-Ping
    Kong, Pei-Yan
    Zhang, Xi
    Gao, Lei
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2015, 9 (03) : 850 - 852
12345