INTESTINAL-ABSORPTION OF INORGANIC MERCURY IN RAT

被引：13
|
作者：
PIOTROWSKI, JK [1 ]
SZYMANSKA, JA [1 ]
SKRZYPINSKAGAWRYSIAK, M [1 ]
KOTELO, J [1 ]
SPORNY, S [1 ]
机构：
[1] MED ACAD LODZ,DEPT PATHOL,PL-90141 LODZ,POLAND
来源：
PHARMACOLOGY & TOXICOLOGY | 1992年 / 70卷 / 01期
关键词：
D O I：
10.1111/j.1600-0773.1992.tb00426.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Hg-203-Mercuric chloride was administered intragastrically to female rats. The absorption rate evaluated for a broad range of doses was found constant for low and medium range, and higher for high doses. Mercury was determined in internal organs and intestines. The time-course of intestinal mercury indicated that a deposit formed initially in the mucosa was further absorbed into the circulation. No indication was found of a protection mechanism based on exfoliation of the mucosal deposits of metal.
引用
收藏
页码：53 / 55
页数：3
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