Crystal structure of ethyl 2-cyano-3-[(1-ethoxyethylidene)amino]-5-(3-methoxy-phenyl)-7-methyl-5H-1,3-thiazolo[3,2-a]-pyrimidine-6-carboxylate

In the title compound, C22H24N4O4S, the central pyrimidine ring adopts a sofa conformation with the ring -junction N atom displaced by 0.2358 (6) angstrom from the mean plane of the remaining ring atoms. The 3-methoxyphenyl ring, at the chiral C atom opposite the other N atom, is positioned axially and is inclined to the thiazolopyrimidine ring with a dihedral angle of 83.88 (7)degrees. The thiazole ring is essentially planar (r.m.s. deviation = 0.0034 A). In the crystal, pairs of weak C-H center dot center dot center dot O "0 hydrogen bonds link molecules related by twofold rotation axes to form R22(8) rings, which in turn are linked by weak C-H center dot center dot center dot N interactions, forming ribbons along [110]. In addition, pi-pi stacking interactions [centroid-centroid 2. distance = 3.5744 (15) angstrom] connect the ribbons, forming slabs lying parallel to (001).