ACYCLIC ANALOGS OF 3'-AZIDO-3'-DEOXYTHYMIDINE AS POTENTIAL ANTIVIRAL AGENTS - NUCLEOSIDE SYNTHESIS BY MICHAEL ADDITION

被引：56
|
作者：
SCHEINER, P
GEER, A
BUCKNOR, AM
IMBACH, JL
SCHINAZI, RF
机构：
[1] UNIV MONTPELLIER 2, CHIM BIOORGAN LAB, F-34060 MONTPELLIER, FRANCE
[2] EMORY UNIV, VET ADM MED CTR, DECATUR, GA 30033 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 01期
关键词：
D O I：
10.1021/jm00121a015
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：73 / 76
页数：4
相关论文
共 50 条
  • [1] SYNTHETIC AND ANTIVIRAL STUDIES OF CERTAIN ACYCLIC 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT) ANALOGS
    LEE, KH
    CHEN, YL
    HUANG, BR
    TZENG, CC
    ZHU, QY
    CHOU, TC
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 1991, 10 (06): : 1407 - 1416
  • [2] 3'-AZIDO-3'-DEOXYTHYMIDINE AND ACYCLOVIR - ANTIVIRAL NUCLEOSIDE ANALOGS WITH UNUSUAL CELL-MEMBRANE PERMEATION PROPERTIES
    ZIMMERMAN, TP
    PRUS, KL
    MAHONY, WB
    DOMIN, BA
    PURINE AND PYRIMIDINE METABOLISM IN MAN VI, PT B: BASIC RESEARCH AND EXPERIMENTAL BIOLOGY, 1989, 253 : 399 - 406
  • [3] SYNTHESIS AND ANTIVIRAL STUDY OF ACYCLIC ANALOGS OF 3'-AZIDO, 3'-AMINO, AND 3'-FLUORO-3'-DEOXYTHYMIDINE, AND OF HEPT ANALOGS
    TRINH, MC
    FLORENT, JC
    GRIERSON, DS
    MONNERET, C
    SYNTHESIS-STUTTGART, 1994, (09): : 939 - 943
  • [4] Transport of the antiviral nucleoside analogs 3'-azido-3' deoxythymidine and 2',3'-dideoxycytidine by a recombinant nucleoside transporter (rCNT) expressed in Xenopus laevis oocytes
    Yao, SYM
    Cass, CE
    Young, JD
    MOLECULAR PHARMACOLOGY, 1996, 50 (02) : 388 - 393
  • [5] 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT) AND ACYCLOVIR (ACV) - ANTIVIRAL NUCLEOSIDE ANALOGS WITH UNUSUAL CELL-MEMBRANE PERMEATION PROPERTIES
    ZIMMERMAN, TP
    PRUS, KL
    MAHONY, WB
    DOMIN, BA
    PEDIATRIC RESEARCH, 1988, 24 (01) : 142 - 142
  • [6] AN EFFICIENT SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT)
    CZERNECKI, S
    VALERY, JM
    SYNTHESIS-STUTTGART, 1991, (03): : 239 - 240
  • [7] A SIMPLIFIED SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE (AZT)
    MANDAL, SB
    ACHARI, B
    JOURNAL OF CHEMICAL RESEARCH-S, 1993, (08): : 326 - 327
  • [8] Synthesis and properties of 3′-azido-3′-deoxythymidine derivatives of glycerolipids
    D. V. Lonshakov
    E. O. Baranova
    A. I. Lyutik
    N. S. Shastina
    V. I. Shvets
    Pharmaceutical Chemistry Journal, 2011, 44 : 557 - 563
  • [9] Synthesis of 3′-Azido-3′-Deoxythymidine-α-Hydroxyphosphonate Derivatives
    Ren Yujie
    Sun Xiaobin
    Shu Chunfeng
    Xi Caiming
    Xiao Qiang
    Liu Ma
    Zhao Yufen
    ACTA CHIMICA SINICA, 2009, 67 (15) : 1822 - 1824
  • [10] Synthesis of tritium-labelled 3′-azido-3′-deoxythymidine
    Sidorov, GV
    Zverkov, YB
    Myasoedov, NF
    Jask, MV
    Skoblov, YS
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2003, 46 (07): : 669 - 676
12345