IMPROVED ANTICONVULSANT ACTIVITY OF PHENYTOIN BY A REDOX BRAIN DELIVERY SYSTEM .3. BRAIN UPTAKE AND PHARMACOLOGICAL EFFECTS

被引：20
|
作者：
SHEK, E
MURAKAMI, T
NATH, C
POP, E
BODOR, NS
机构：
[1] UNIV FLORIDA,J HILLIS MILLER HLTH CTR,CTR DRUG DESIGN & DELIVERY,BOX J-497,GAINESVILLE,FL 32610
[2] UNIV FLORIDA,J HILLIS MILLER HLTH CTR,COLL PHARM,DEPT MED CHEM,GAINESVILLE,FL 32610
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1989年 / 78卷 / 10期
关键词：
D O I：
10.1002/jps.2600781012
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：837 / 843
页数：7
相关论文
共 50 条
  • [1] IMPROVED ANTICONVULSANT ACTIVITY OF PHENYTOIN BY A REDOX BRAIN DELIVERY SYSTEM .2. STABILITY IN BUFFERS AND BIOLOGICAL-MATERIALS
    MURAKAMI, T
    SHEK, E
    POP, E
    BODOR, N
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1989, 78 (09) : 732 - 737
  • [2] IMPROVED DELIVERY THROUGH BIOLOGICAL-MEMBRANES .27. IMPROVED ANTICONVULSANT ACTIVITY OF PHENYTOIN BY A REDOX BRAIN DELIVERY SYSTEM .1. SYNTHESIS AND SOME PROPERTIES OF THE DIHYDROPYRIDINE DERIVATIVES
    POP, E
    SHEK, E
    MURAKAMI, T
    BODOR, NS
    JOURNAL OF PHARMACEUTICAL SCIENCES, 1989, 78 (08) : 609 - 616
  • [3] INTRAVENOUS PHENYTOIN AND PHENOBARBITAL - BRAIN CONTENT AND ANTICONVULSANT ACTIVITY
    LEPPIK, IE
    SHERWIN, AL
    CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1977, 4 (03) : 223 - 223
  • [4] IMPROVED BRAIN DELIVERY AND IN-VITRO ACTIVITY OF ZIDOVUDINE THROUGH THE USE OF A REDOX CHEMICAL DELIVERY SYSTEM
    MIZRACHI, Y
    RUBINSTEIN, A
    HARISH, Z
    BIEGON, A
    ANDERSON, WR
    BREWSTER, ME
    AIDS, 1995, 9 (02) : 153 - 158
  • [5] Nanostructured lipid carriers-mediated brain delivery of carbamazepine for improved in vivo anticonvulsant and anxiolytic activity
    Khan, Namrah
    Shah, Fawad Ali
    Rana, Isra
    Ansari, Muhammad Mohsin
    Din, Fakhar ud
    Rizvi, Syed Zaki Husain
    Aman, Waqar
    Lee, Gwan-Yeong
    Lee, Eun-Sun
    Kim, Jin-Ki
    Zeb, Alam
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2020, 577
  • [6] RELATION OF PLASMA AND BRAIN CONCENTRATIONS OF THE ANTICONVULSANT AMELTOLIDE TO ITS PHARMACOLOGICAL EFFECTS
    LEANDER, JD
    PARLI, CJ
    POTTS, B
    LODGE, D
    EPILEPSIA, 1992, 33 (04) : 696 - 704
  • [7] Improved brain uptake and pharmacological activity of dalargin using a peptide-vector-mediated strategy
    Rousselle, C
    Clair, P
    Smirnova, M
    Kolesnikov, Y
    Pasternak, GW
    Gac-Breton, S
    Rees, AR
    Scherrmann, JM
    Temsamani, J
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2003, 306 (01): : 371 - 376
  • [8] ANTICONVULSANT MODIFICATION OF TRIPELENNAMINE EFFECTS ON ELECTROGRAPHIC ACTIVITY OF CAT BRAIN
    FAINGOLD, CL
    BERRY, CA
    NEUROPHARMACOLOGY, 1973, 12 (04) : 383 - 390
  • [9] IMPROVED BRAIN DELIVERY OF ANTIVIRAL AGENTS THROUGH THE USE OF REDOX TARGETING
    BREWSTER, ME
    BODOR, N
    ADVANCED DRUG DELIVERY REVIEWS, 1994, 14 (2-3) : 177 - 197
  • [10] Improved brain delivery of antiviral agents through the use of redox targeting
    Brewster, M.E., 1600, Publ by Elsevier Science Publishers B.V., Amsterdam, Netherlands (14): : 2 - 3
12345