PROGRESSION OF OPTIC NEURITIS TO MULTIPLE-SCLEROSIS - A PROSPECTIVE-STUDY IN AN ITALIAN POPULATION

被引：5

作者：

MAPELLI, G ^{[1
]}

PAVONI, M ^{[1
]}

DEPALMA, P ^{[1
]}

MODESTINO, R ^{[1
]}

PAVONI, V ^{[1
]}

机构：

[1] UNIV FERRARA,INST OPHTHALMOL,I-44100 FERRARA,ITALY

来源：

NEUROEPIDEMIOLOGY | 1991年 / 10卷 / 03期

关键词：

OPTIC NEURITIS; MULTIPLE SCLEROSIS;

D O I：

10.1159/000110256

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We prospectively studied 40 patients with uncomplicated optic neuritis (ON) to determine the risk of subsequent multiple sclerosis (MS). All patients were followed for at least 12 years. Ten patients (25%) developed MS. Seven of these 10 patients developed MS within 2 years. Both sexes were at high risk if ON occurred between the ages of 21 and 40. There was an overall increased risk of MS with recurrent ON. The course of MS appeared to be fairly benign during the period of observation.

引用

页码：117 / 121

页数：5

共 50 条

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COHEN, MM
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[J]. NEUROLOGY, 1979, 29 (02) : 208 - 213
[2] ACUTE OPTIC NEURITIS - A PROSPECTIVE-STUDY OF RISK-FACTORS FOR MULTIPLE-SCLEROSIS
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[3] RISK OF DEVELOPING MULTIPLE-SCLEROSIS AFTER UNCOMPLICATED OPTIC NEURITIS - A LONG-TERM PROSPECTIVE-STUDY
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