SEQUENCE-ANALYSIS AND EXCLUSION OF PHOSDUCIN AS THE GENE FOR THE RECESSIVE RETINAL DEGENERATION OF THE ABYSSINIAN CAT

被引：5
|
作者：
GORIN, MB
TO, AC
NARFSTROM, K
机构：
[1] UNIV PITTSBURGH,SCH MED,DEPT HUMAN GENET,PITTSBURGH,PA
[2] GRAD SCH PUBL HLTH,PITTSBURGH,PA
[3] SWEDISH UNIV AGR SCI,DEPT MED & SURG,UPPSALA,SWEDEN
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1260卷 / 03期
关键词：
RETINAL DEGENERATION; PHOSDUCIN; CANDIDATE GENE; (CAT);
D O I：
10.1016/0167-4781(94)00231-Q
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Phosducin was evaluated as a candidate gene for the recessive retinal degeneration in the Abyssinan cat, rdAc, using reverse transcription and polymerase chain amplification. The nucleotide sequence of the cat phosducin coding region was determined except for 23 bp at the 5' end. Single-strand conformation analysis of a silent polymorphism within the coding region established the nonlinkage of the phosducin gene with the rdAc locus.
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页码：323 / 327
页数：5
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