The Level Of Disaggregation Control Of Blood Vessels Over Neutrophils In Patients With Abdominal Obesity And Dyslipidemia

High-calorie diet against the background of low physical activity in the bulk of the population of developed countries lead to a widespread prevalence of abdominal obesity and dyslipidemia. A serious problem of this category of patients is the high frequency of thrombosis of different localization. This is caused by the formation in these patients of vasopathy with a weakening of the hemostatic properties of the vessels. The goal is to find out the level of disaggregation capacity of blood vessels in patients with abdominal obesity and dyslipidemia with respect to neutrophils. We examined 41 patients of the second mature age (mean age 49.2 +/- 1.8 years) with abdominal obesity with dyslipidemia. The control group was composed of 26 clinically healthy people of the same age. All the examined persons gave written informed consent on participation in the research. There were applied biochemical, hematological and statistical methods of investigation. High thromboses' frequency of various localizations at abdominal obesity with dyslipidemia is closely connected with angiopathy development against their background. Weakening of plasma antioxidant protection with activation of lipids' peroxidation processes in it leading to alteration of vascular wall, is noted in conditions of abdominal obesity with dyslipidemia. The persons with arterial hypertension and abdominal obesity with dyslipidemia are detected to have evident weakening of disaggregating vascular impacts of vascular wall on strengthening aggregative ability of neutrophils. In the result of it given patients get sharply increased risk of thromboses of any localization which can lead to invalidism and lethal outcome.