SCHIZOPHRENIA AND AMYOTROPHIC-LATERAL-SCLEROSIS

被引:15
|
作者
HOWLAND, RH
机构
[1] Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA
关键词
D O I
10.1016/0010-440X(90)90039-U
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Schizophrenia and amyotrophic lateral sclerosis (ALS) are central nervous system (CNS) disorders of unknown etiology. The association of these two disorders has been infrequently reported in the literature, but is not a rare occurrence. Various neuromuscular abnormalities involving the alpha-motor neuron have been described in some patients with schizophrenia. This report reviews the literature on schizophrenia, psychosis, and ALS and describes two additional cases of schizophrenia associated with ALS. The possibility that the neuromuscular dysfunction in schizophrenia may predispose to ALS and provide an explanation for the association of these two disorders is discussed. Additional research data are needed to test this hypothesis. © 1990.
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页码:327 / 336
页数:10
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