INHIBITION OF TOXOPLASMA-GONDII PROTEIN-SYNTHESIS BY AZITHROMYCIN

被引：32
|
作者：
BLAIS, J
GARNEAU, V
CHAMBERLAND, S
机构：
[1] UNIV LAVAL,CTR HOSP,CTR RECH,INFECTIOL LAB & SERV,QUEBEC CITY G1V 4G2,QUEBEC,CANADA
[2] UNIV LAVAL,FAC MED,DEPT MICROBIOL,QUEBEC CITY G1V 4G2,QUEBEC,CANADA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1993年 / 37卷 / 08期
关键词：
D O I：
10.1128/AAC.37.8.1701
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Azithromycin was shown to specifically inhibit the protein synthesis of Toxoplasma gondii in experimental systems by using free tachyzoites and T. gondii-infected mouse macrophages. RNA synthesis of the parasite was not affected by azithromycin. Inhibition of protein synthesis was also proportional to the relative anti-Toxoplasma activity of three macrolides.
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页码：1701 / 1703
页数：3
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