THE BETA-ENDORPHIN RESPONSE TO PRENATAL STRESS DURING POSTNATAL-DEVELOPMENT IN THE RAT

被引：16
|
作者：
SANCHEZ, MD
MILANES, MV
FUENTE, T
LAORDEN, ML
机构：
[1] UNIV MURCIA, FAC MED, DEPT PHYSIOL & PHARMACOL, PHARMACOL UNIT, MURCIA, SPAIN
[2] CSV ARRIXACA HOSP, DEPT NUCL MED, MURCIA, SPAIN
来源：
DEVELOPMENTAL BRAIN RESEARCH | 1993年 / 74卷 / 01期
关键词：
PRENATAL STRESS; OFFSPRING; HYPOTHALAMIC BETA-ENDORPHIN LEVEL;
D O I：
10.1016/0165-3806(93)90095-R
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We examined the hypothalamic beta-endorphin (B-END) levels in offspring (postnatal day 10) from stressed female rats in different period of gestation: group 1, restraint stress from day 2 to 6; group 2, from day 7 to 11 and group 3, from day 2 to 16. The hypothalamic levels of B-END in the offspring from group 1 were significantly (P < 0.001) higher to that obtained in the control. Similar results were obtained in the group 2. However, in rat pups from female stressed during 15 days of gestation hypothalamic levels of B-END were similar to control group.
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页码：142 / 145
页数：4
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