GEOSEQ - A PASCAL PROGRAM TO CALCULATE STATISTICAL GEOMETRY PARAMETERS OF ALIGNED NUCLEIC-ACID SEQUENCES

被引:0
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作者
LOPEZBUENO, JA [1 ]
MOYA, A [1 ]
机构
[1] FAC BIOL VALENCIA,DEPT GENET,C DR MOLINER 50,E-46100 BURJASSOT,SPAIN
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中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Statistical geometry in sequence space is a statistical method used mainly to determine the topology of the divergence (i.e. tree, bundle or net) of a set of aligned sequences by combining horizontal and vertical positional information. GEOSEQ is a documented program written in Pascal that calculates the statistical geometry parameters necessary to choose between phylogenetic topologies. The input file is an optimal alignment of nucleic acid sequences in PHYLIP format (v. 3.3) with a first line containing information regarding sequences as well as some options. In order to check the randomization level associated with the obtained topology, the program has been implemented with a random generator of sequences under specified set conditions.
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页码:385 / 388
页数:4
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