Tissue Doppler Imaging and Doppler Studies in Patients with Transmural and Non-transmural Myocardial Infarction

Background- Myocardial longitudinal shortening play an important role in cardiac contraction(1,2). Tissue velocity imaging (TVI) is an ultrasonographic technique that measure myocardial motion and providing a quantitative agreement of left ventricular regional myocardial function in different modalities (3). The present review discusses the most recent development in the application of TDI in coronary artery disease. Methods- Seventy patients with myocardial infarction (transmural and nontransmural) were included in the study. These subjects were diagnosed with recent myocardial infarction according to electrocardiography, cardiac enzymes and history. The basal segments of septal wall(septal side of mitral annulus) and basal segment of base of RV free wall were examined for tissue Doppler study with complete transthoracic echocardiography study. Results- Mean age in group of inferior MI, anterior MI and non Q wave MI are as follows: 61.87 +/- 10.7, 57.04 +/- 10.7, 58.45 +/- 9.2. Sm was significantly reduced in anterior MI groups than non Q wave MI ( PV= 0.01). In patients with inferior myocardial infarction 88% of patients had left ventricular ejection fraction (LVEF)> 45% and in patients with anterior MI 18.2% patients had EF>45%. In non Q wave MI groups 60% patients had LVEF > 45%. Conclusion- Except for Sm, other TDI parameters had no significant difference between two groups (transmural and nontransmural infarction) but it has significant changes in reduced left ventricle function and could be of determinants for prognosis.