REVERSAL OF MULTIDRUG-RESISTANCE TO CANCER-CHEMOTHERAPY

被引：0
|
作者：
LEYLANDJONES, B
DALTON, W
FISHER, GA
SIKIC, BI
机构：
[1] UNIV ARIZONA,ARIZONA CANC CTR,TUCSON,AZ 85721
[2] STANFORD UNIV,MED CTR,STANFORD,CA 94305
来源：
CANCER | 1993年 / 72卷 / 11期
关键词：
MULTIDRUG RESISTANCE; CALCIUM CHANNEL BLOCKERS; CYCLOSPORINES;
D O I：
10.1002/1097-0142(19931201)72:11+<3484::AID-CNCR2820721615>3.0.CO;2-L
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In the past few years, the role of membrane-bound transport genes in human disease has been increasingly recognized and understood. Of these genes, the p170 membrane glycoprotein may function as an outward transport pump for many cancer chemotherapeutic drugs associated with the multidrug resistance phenotype. This article reviews the different classes of the current major modulators of multidrug resistance.
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页码：3484 / 3488
页数：5
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