BIOMAGNIFICATION OF BIOASSAY DERIVED 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN EQUIVALENTS

被引：27
|
作者：
JONES, PD
ANKLEY, GT
BEST, DA
CRAWFORD, R
DEGALAN, N
GIESY, JP
KUBIAK, TJ
LUDWIG, JP
NEWSTED, JL
TILLITT, DE
VERBRUGGE, DA
机构：
[1] MICHIGAN STATE UNIV,INST ENVIRONM TOXICOL,E LANSING,MI 48824
[2] US EPA,ENVIRONM RES LAB,DULUTH,MN 55804
[3] US FISH & WILDLIFE SERV,E LANSING,MI 48823
[4] ECOL RES SERV,ANN ARBOR,MI 48104
[5] US FISH & WILDLIFE SERV,NATL FISHERIES CONTAMINANT RES LAB,COLUMBIA,MO 65201
来源：
CHEMOSPHERE | 1993年 / 26卷 / 06期
关键词：
D O I：
10.1016/0045-6535(93)90206-K
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
In recent years contamination of the Great Lakes ecosystem with planar chlorinated hydrocarbons (PCHs) has attracted considerable concern due to their known reproductive and teratogenic effects. The H4IIE bioassay has been standardized as a means of measuring the biological potency of a PCH mixture as 2,3,7,8-tetrachloro-p-dibenzodioxin equivalents (TCDD-EQ). Using this bioassay we have investigated the biomagnification of TCDD-EQ in a semi-closed ecosystem. The biomagnification of TCDD-EQ is demonstrated and results indicate that the food chain is the major pathway for TCDD-EQ through this ecosystem. The H4IIE assay system is demonstrated to be a viable integrative measure of the total concentration of TCDD-EQ in different trophic levels.
引用
收藏
页码：1203 / 1212
页数：10
相关论文
共 50 条
  • [1] PHOTOLYSIS OF "2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN
    PLIMMER, JR
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1974, : 29 - 29
  • [2] RADIOIMMUNOASSAY FOR "2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN
    ALBRO, PW
    CHAE, K
    LUSTER, M
    MCKINNEY, JD
    CHAUDHARY, S
    CLARK, G
    FAWKES, J
    CORBETT, J
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 1977, 20 (OCT) : 247 - 247
  • [3] Bioassay for determining 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEs) in human hepatoma HepG2 cells
    Wiebel, FJ
    Wegenke, M
    Kiefer, F
    [J]. TOXICOLOGY LETTERS, 1996, 88 (1-3) : 335 - 338
  • [4] Establishment of a simple cleanup procedure and bioassay for determining 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity equivalents of environmental samples
    Schwirzer, SMG
    Hofmaier, AM
    Kettrup, A
    Nerdinger, PE
    Schramm, KW
    Thoma, H
    Wegenke, M
    Wiebel, FJ
    [J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 1998, 41 (01) : 77 - 82
  • [5] APPLICATION OF A BIOASSAY FOR DETERMINATION OF PICOGRAM LEVELS OF "2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD)
    WIEBEL, FJ
    GEBEFUGI, I
    [J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1978, 302 : R23 - R23
  • [6] EMBRYONIC MORTALITY, BIOASSAY DERIVED 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN EQUIVALENTS, AND ORGANOCHLORINE CONTAMINANTS IN PACIFIC SALMON FROM LAKE-ONTARIO
    SMITH, IR
    MARCHANT, B
    VANDENHEUVEL, MR
    CLEMONS, JH
    FRIMETH, J
    [J]. JOURNAL OF GREAT LAKES RESEARCH, 1994, 20 (03) : 497 - 509
  • [7] 2,3,7,8-tetrachlorodibenzo-p-dioxin and the viral infection
    Fiorito, Filomena
    Santamaria, Rita
    Irace, Carlo
    De Martino, Luisa
    Iovane, Giuseppe
    [J]. ENVIRONMENTAL RESEARCH, 2017, 153 : 27 - 34
  • [8] 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN - ENVIRONMENTAL CHEMISTRY
    MILLER, GC
    ZEPP, RG
    [J]. ACS SYMPOSIUM SERIES, 1987, 338 : 82 - 93
  • [9] Cutaneous elimination of 2,3,7,8-tetrachlorodibenzo-p-dioxin
    Geusau, A
    Tschachler, E
    Meixner, M
    Päpke, O
    Stingl, G
    McLachlan, M
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2001, 145 (06) : 938 - 943
  • [10] 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN EQUIVALENTS IN TISSUES OF BIRDS AT GREEN BAY, WISCONSIN, USA
    JONES, PD
    GIESY, JP
    NEWSTED, JL
    VERBRUGGE, DA
    BEAVER, DL
    ANKLEY, GT
    TILLITT, DE
    LODGE, KB
    NIEMI, GJ
    [J]. ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 1993, 24 (03) : 345 - 354
12345