HYPERTRIGLYCERIDEMIA MAY BE SEVERE IN CML PATIENTS TREATED WITH INTERFERON-ALPHA

被引：13

作者：

PENARRUBIA, MJ ^{[1
]}

STEEGMANN, JL ^{[1
]}

LAVILLA, E ^{[1
]}

CASADO, F ^{[1
]}

REQUENA, MJ ^{[1
]}

PICO, M ^{[1
]}

ARRANZ, R ^{[1
]}

FERNANDEZRANADA, JM ^{[1
]}

机构：

[1] HOSP PRINCESA,DEPT HEMATOL,E-28006 MADRID,SPAIN

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 1995年 / 49卷 / 03期

关键词：

CHRONIC MYELOID LEUKEMIA; INTERFERON; TRIGLYCERIDES;

D O I：

10.1002/ajh.2830490311

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We analyzed serum triglyceride (TG) levels in 22 chronic myeloid leukemia (CML) patients treated with interferon-alpha (IFN-alpha). Hypertriglyceridemia was present in one-half of patients at diagnosis, and IFN-alpha treatment was associated with a further increase in 90% of the total group of patients. This increase was maximal during the first months of therapy. Four patients (18%) reached levels higher than 1,000 mg/dl. This is the first report describing this secondary effect in CML patients treated with IFN-alpha. (C) 1995 Wiley-Liss, Inc.

引用

页码：240 / 241

页数：2

共 50 条

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