Regulation of context-specific gene expression by posttranscriptional switches

被引：1
|
作者：
Sundaram, Gopinath M. [1 ]
Sampath, Prabha [1 ,2 ]
机构：
[1] ASTAR, Inst Med Biol, Singapore, Singapore
[2] Natl Univ Singapore, Dept Biochem, Yong Loo Lin Sch Med, Singapore, Singapore
来源：
TRANSCRIPTION-AUSTIN | 2013年 / 4卷 / 05期
关键词：
RNA binding proteins; post-transcriptional switch; untranslated regions of mRNA; exonic miRNA; miRNAs; wound healing; non-coding RNAs;
D O I：
10.4161/trns.26393
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Post-transcriptional control of mRNA is a vital step in the regulation of gene expression. Highly specific combinations of RNA-binding-proteins (RBPs) and microRNAs conjointly contribute to the complexity of post-transcriptional control of mRNAs. Post-transcriptional switches regulated by RBPs control context-specific expression of two alternative gene products from a single transcript.
引用
收藏
页码：213 / 216
页数：4
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