Adjuvant chemotherapy in patients with completely resected non-small cell lung cancer

被引：40
|
作者：
Pirker, Robert [1 ]
机构：
[1] Med Univ Vienna, Dept Med 1, Wahringer Gurtel 18-20, A-1090 Vienna, Austria
来源：
TRANSLATIONAL LUNG CANCER RESEARCH | 2014年 / 3卷 / 05期
关键词：
Adjuvant; chemotherapy; non-small cell lung cancer (NSCLC); resection;
D O I：
10.3978/j.issn.2218-6751.2014.09.13
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Adjuvant chemotherapy has been established as a standard for patients with completely resected non-small cell lung cancer (NSCLC). Adjuvant chemotherapy increased the 5-year survival rates by 4% to 15% within randomized trials and, based on a meta-analysis of five cisplatin-based trials, by 5.4%. Adjuvant chemotherapy consists of a cisplatin-based doublet, preferentially cisplatin plus vinorelbine. Future improvements in outcome of adjuvant therapy are expected by customized chemotherapy and the integration of targeted therapies or immunotherapy.
引用
收藏
页码：305 / 310
页数：6
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