The Use of Induced Pluripotent Stem Cells in Medicine

被引：0
|
作者：
Guran, Sefik [1 ]
Coban, Zehra Dilsad [1 ]
机构：
[1] Gulhane Askeri Tip Akad, Tibbi Biyol Anabilim Dali, TR-06018 Ankara, Turkey
来源：
ERCIYES MEDICAL JOURNAL | 2012年 / 34卷 / 04期
关键词：
Embryonal carcinoma stem cells; induced pluripotent stem cell; regenerative medicine; gene;
D O I：
10.5152/etd.2012.49
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Induced pluripotent stem cells with self renewal and differentiation abilities were established from mature cells by transcription factors. These cells may be used in regenerative medicine as embryonic stem cells. Recently a mutated gene in a cell obtained from a mouse which had a genetic disease was corrected by gene targeting techniques. These cells were converted into induced pluripotent stem cell by using transcription factor genes and transferred into the same mouse. As a result, the clinical findings of genetic disease mostly disappeared in the mouse. In this manuscript, the new uses of induced pluripotent stem cells in medicine were discussed.
引用
收藏
页码：184 / 187
页数：4
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