BIOSENSOR MONITORING OF BLOOD LACTATE DURING OPEN-HEART-SURGERY

被引：9
|
作者：
KYROLAINEN, M
HAKANSON, H
EKROTH, R
MATTIASSON, B
机构：
[1] Department of Biotechnology, Chemical Centre, Lund University, S-221 00 Lund
来源：
ANALYTICA CHIMICA ACTA | 1993年 / 279卷 / 01期
关键词：
BIOSENSORS; ENZYMATIC METHODS; BLOOD; ENZYME REACTOR; LACTATE; SURGERY;
D O I：
10.1016/0003-2670(93)85077-W
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
An on-line monitoring system for lactate in blood is described. The system consists of a sampling unit allowing dilution at the sampling point, a sample treatment unit for dialysis of the sample and an enzyme reactor with immobilized lactate oxidase. A Clark electrode is used as transducer. The enzyme preparation shows high storage stability and good operational stability. The system was used, during and after open-heart surgery, to follow fluctuation in the concentrations Of L-lactate in blood being pumped to and from the brain. A small difference of approximately 0.3-0.5 mM was monitored.
引用
收藏
页码：149 / 153
页数：5
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