H1N1 Virus Production and Infection

被引：3
|
作者：
Zhao, Binbin [1 ,3 ,4 ]
Shan, Jiaoyu [1 ,2 ]
Xiong, Rui [1 ]
Xu, Ke [1 ]
Li, Bin [3 ,4 ]
机构：
[1] Univ Chinese Acad Sci, Chinese Acad Sci, Inst Pasteur Shanghai, CAS Ctr Excellence Mol Cell Sci,CAS Key Lab Mol V, Shanghai, Peoples R China
[2] Xinjiang Med Univ, Human Parasitol Dept, Basic Med Coll, Urumqi, Peoples R China
[3] Shanghai Jiao Tong Univ, Sch Med, Shanghai Inst Immunol, Shanghai, Peoples R China
[4] Shanghai Jiao Tong Univ, Sch Med, Dept Immunol & Microbiol, Shanghai, Peoples R China
来源：
BIO-PROTOCOL | 2018年 / 8卷 / 20期
基金：
中国国家自然科学基金;
关键词：
Influenza A virus; Infected mouse model; H1N1; Virus production; Plaque assay;
D O I：
10.21769/BioProtoc.3062
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Influenza A virus is a member of orthomyxoviridae family causing wide-spread infections in human respiratory tract. Mouse infection model is widely used in antiviral research and pathogenesis study against influenza A virus. Here, we report a protocol in infected mice with different virus doses and strains to explore how an inhibitor of lysine-specific demethylase (LSD1) impacts disease progression.
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页数：8
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