CELL INJURY AND DEATH CAUSED BY BACTERIAL PROTEIN TOXINS

被引:6
|
作者
DONELLI, G
FIORENTINI, C
机构
[1] Department of Ultrastructures, Istituto Superiore di Sanità
关键词
CLOSTRIDIUM-DIFFICILE TOXIN-A; ESCHERICHIA-COLI CNF1; CYTOSKELETON; CYTOTOXICITY;
D O I
10.1016/0378-4274(92)90249-J
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Bacterial protein toxins, such as Clostridium diffscile toxin A and the Escherichia coli cytotoxic necrotizing factor 1 are known to exert their cytotoxic action via a modification of some cytoskeletal components. The changes in actin organization caused by these toxins appear to be the primary events in the mechanism leading to cell death.
引用
收藏
页码:695 / 699
页数:5
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