INTERLEUKIN-6 LEVELS IN THE CEREBROSPINAL-FLUID OF PATIENTS WITH MULTIPLE-SCLEROSIS

被引：0
|
作者：
ARAGA, S [1 ]
TAKAI, H [1 ]
TAKAHASHI, K [1 ]
机构：
[1] TOTTORI UNIV,FAC MED,INST NEUROL SCI,DIV NEUROL,YONAGO,TOTTORI 683,JAPAN
来源：
JAPANESE JOURNAL OF PSYCHIATRY AND NEUROLOGY | 1991年 / 45卷 / 04期
关键词：
ENZYME-LINKED IMMUNOSORBENT ASSAY; BIOASSAY; CEREBROSPINAL FLUID AND RECOMBINANT INTERLEUKIN-6;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We developed the competitive enzyme-linked immunosorbent assay for interleukin-6 (IL-6). The detection limit was 30 pg per ml. Using this method, we examined the IL-6 levels in the cerebrospinal fluid of 10 patients with multiple sclerosis (MS) and 12 age-matched normal controls. IL-6 was detected in 6 out of 10 patients with MS. There was no significant correlation between the IL-6 levels and other parameters, including IgG, IgG index, cell counts, total protein and albumin in the CSF. Our results suggest that IL-6 detected in the MS-CSF may have no correlation to the immunological processes.
引用
收藏
页码：879 / 883
页数：5
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