CEREBRAL BLOOD-FLOW IN SUBCORTICAL GLOBAL APHASIA - PERISYLVIAN CORTICAL HYPOPERFUSION AS A CRUCIAL ROLE

被引:20
|
作者
OKUDA, B [1 ]
TANAKA, H [1 ]
TACHIBANA, H [1 ]
KAWABATA, K [1 ]
SUGITA, M [1 ]
机构
[1] HYOGO MED UNIV,DEPT REHABIL,NISHINOMIYA,HYOGO,JAPAN
关键词
APHASIA; CEREBRAL BLOOD FLOW; DIASCHISIS; CEREBROVASCULAR DISORDERS; LANGUAGE;
D O I
10.1161/01.STR.25.7.1495
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background and Purpose Global aphasia after subcortical stroke is very rare, and its pathophysiology remains unsolved. To clarify the mechanism underlying subcortical global aphasia, we investigated lesion sites and cerebral blood flow in patients with subcortical global aphasia and nonaphasic patients with subcortical stroke. Methods We examined four patients with global aphasia and four nonaphasic patients. Language testing was performed more than 4 weeks after the onset. Measurement of cerebral blood flow was done between 35 and 75 days after stroke by using single-photon emission computed tomography (SPECT) with N-isopropyl-p[I-123]iodoamphetamine as a tracer and three-dimensional surface display generated from SPECT.
引用
收藏
页码:1495 / 1499
页数:5
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