LIPID PEROXIDATION AND LIPID PROFILE IN PATIENTS WITH SENILE CATARACT

Lipid peroxidation products and biochemical parameters like fasting blood sugar and lipid profile were estimated in serum of 40 senile cataract cases (45-60 years) and 40 persons of age and sex matched healthy controls. Plasma Thiobarbituric acid reactive substances (TBARS) levels [as Malondialdehyde (MDA)] were significantly higher in patients with senile cataract (573 +/- 64.4nmo1/dl, P<0.001) as compared to healthy controls (378 +/- 31.31 nmol/dl). Serum cholesterol, Triglycerides, LDLC, VLDLC levels were increased as compared to controls. But HDLC levels were decreased in senile cataract patients as compared to controls. No significant change was observed in FBS values. The present study shows that the oxidative stress may play an important role in the senile cataract.