Here with are the results of clinical studies the Authors carried out on 50 menopausal women treated with a dietary supplement which contained phytoestrogens and dioscorea villosa. Each patient, during the treatment, was subjected to a clinical follow- up and particularly to a check-up of the endometrial ecopattern. Patients lost for adverse side effects was very low (8%). In 80% of the cases, there were positive response on hot flushes, osteoporosis, nervous system, vaginal dryness and without any outbreak of serious pathology.