RELATIONSHIP BETWEEN CHIMPANZEE RH-LIKE GENES AND THE R-C-E-F BLOOD-GROUP SYSTEM

被引：0
|
作者：
SALVIGNOL, I
BLANCHER, A
CALVAS, P
SOCHA, WW
COLIN, Y
CARTRON, JP
RUFFIE, J
机构：
[1] CHU PURPAN,CTR REG TRANSFUS SANGUINE,F-31052 TOULOUSE,FRANCE
[2] COLL FRANCE,ANTHROPOL PHYS LAB,F-75231 PARIS 05,FRANCE
[3] NYU MED CTR,LEMSIP,NEW YORK,NY 10016
[4] INST NATL TRANSFUS SANGUINE,INSERM,U76,UNITE RECH,PARIS,FRANCE
来源：
JOURNAL OF MEDICAL PRIMATOLOGY | 1993年 / 22卷 / 01期
关键词：
MOLECULAR GENETICS; SOUTHERN BLOT; PHYLOGENY; RH GENE HOMOLOGY;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The antigenic closeness between the chimpanzee alloantigen R(c) of the R-C-E-F system, and the human alloantigen Rh(o)(D) suggests a phylogeconnection between their genes. To confirm at the molecular level the common origin of these genes, genomic DNA from 16 unrelated chimpanzees of various R-C-E-F phenotypes were digested by three restriction enzymes and analyzed by Southern blot using a human Rh cDNA probe and three exon-specific probes. Restrictions profiles displayed reach polymorphism. Correlations between some bands and certain R-C-E-F phenotypes demonstrate that the human Rh cDNA probe defines in chimpanzee genomic DNA some genes of the R-C-E-F system.
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页码：19 / 28
页数：10
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